Look, I have to be honest here. CJD runs in my family. It's genetic. I don't know if I carry the marker or not but I've still given up eating animals. Whether it matters or not, being vegan is more in line with my personal values. I'm sick of the beef argument. It's still vital, it's still important and it's still a huge issue by all means. Getting the USDA to test every animal meant for human consumption is still a noble goal. Knowing where your beef came from and how that cow you're about to eat was raised is still important.
But.
Time is running out for us genetic folks. If my body does what my mom's did, I may only be around for another 30 years. We need to focus on finding the cure so that I -- and every other potential genetic case -- can grow to be old. Very old. Sitting in a rocking chair watching great grandchildren old. That's the goal.
So I'm dedicating this blog, and the soon-to-come CURECJD.com to finding the cure. I am no scientist, only one lonely freelance journalist in Phoenix, Arizona with a heavy DNA burden to carry. No beef here. No USDA here. This blog will be about research being done to find the cure for CJD. This blog will be about people working to find the cure for CJD. We can share our opinions and fears here about finding the cure for CJD.
And that's it.
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Besides the results on PPS, I'd like to point out two other results.
Dollinger et al. published on J. Med. Chem. (2006) that bis-acridines exhibit up to 10-fold increase in antiprion potency compared to quinacrine in vitro. Thus, it's interesting to investigate the effects of this drug in vivo.
Moreover, BRNI scientists recently patented a new method for crossing the blood-brain barrier (U.S. patent number 7,220,833, "Artificial Low-Density Lipoprotein Carriers for Transport of Substances Across the Blood-Brain Barrier"). This method may succeed in deliver PPS in the brain without the use of any catheter, and it can also be used to try other drugs that have not been tried yet due to their inability to pass through the BBB.
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